‘Partial inhibition will do the trick as when you reduce one copy of the gene, your fat cells are very much smaller and the pet is lean already.’ The animals not only have less fat, they have significantly more muscle and burn more energy also, said Ming-Jer Tsai.. COUP-TFII plays pivotal part in obesity, metabolic syndrome A protein known to play a role in development and the forming of organs is also a significant factor in the control of obesity and diabetes, said researchers from Baylor College of Medicine in a written report that appears in today’s issue of the journal Cell Metabolism.In the dose-finding research SOUND-C2, 44 of the 362 patients contained in the evaluation discontinued because of adverse occasions. 3 In SOUND-C3, moderate nausea and rash were the most typical side-effects. Adverse occasions of a moderate or more intensity were rare, with anemia , exhaustion , vomiting and nausea becoming the most typical adverse events. To learn more please visit References ClinicalTrials.gov. IFN-free Mixture Therapy in HCV-infected Individuals Treatment-naive:HCVerso1. [Last accessed 12/07/13] ClinicalTrials.gov.