Dry AMD occurs when light-sensitive cells in the center of the retina or macula – called retinal pigment epithelial cells – slowly break gradually blurring central vision. Over time, as less of the macula functions central vision is in in the affected eye. Dry AMD affects 8-9. Zhang in the United States, to a loss of vision in about one in nine patients, and is responsible for 10 % of cases of legal blindness in the United States was.
Silence or off other genes associated with various diseases human clinical trials human clinical trials are currently using RNAi, including therapies for the wet form of AMD, abnormal blood vessels grow treated if start behind the retina at the macula to a very rapid to a very rapid loss of vision occurs. Zhang cautions that these tests to RNAi therapies for wet AMD, need be careful and aware of a possible unintended side effect. If you are genetically susceptible to macular degeneration and to a virus that activates TLR3 suspended, it could lead to the death of cells in the macula, said Zhang.‘We want to to see if we may rescue this a rapidly aging Animal wanted , so we inject stem / progenitors of young, experiments we into the stomachs of 17-day – old progeria mice, ‘said Huard. ‘Typically that Progerie mice were die be around ago 21 to 28 days, but the treated animals living far longer – some of actually than 66 survived lived were also into better overall health. ‘.