So it is vital that you start a healthy lifestyle immediately.. Are You VULNERABLE TO Contracting Gestational Diabetes? Gestational diabetes is certainly a condition which women who previously had not been diagnosed previously with diabetes start exhibiting high blood sugar during their pregnancy. This type of diabetes is normally diagnosed between the 24th and 28th week of a woman’s pregnancy. It really is caused when the woman’s insulin receptors usually do not function correctly.BELLUS Health initiates Stage I clinical research for NRM8499 BELLUS Wellness Inc. announced today that, on March 30, 2010, the business initiated a Stage I clinical research for NRM8499, a prodrug of tramiprosate. NRM8499 is supposed for the treating Alzheimer’s disease. The randomized, double-blind, placebo-controlled research will investigate the basic safety, tolerability and pharmacokinetic profile of NRM8499 in a combined band of up to 84 little and elderly healthy topics. NRM8499 once was identified by BELLUS Wellness as a substance which escalates the brain contact with tramiprosate. Preclinical research conducted in rodents demonstrated that NRM8499 elevated plasma and brain contact with tramiprosate by 1.5 to 3 fold.